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BP-TARGET2021
Intensive post-EVT BP (SBP 100–129) did not reduce radiographic hemorrhage.
TENSION2023
Large-core EVT (ASPECTS 3–5) by NCCT shifted median mRS 5→4; mortality 51%→40%.
SPARCL2006
Atorvastatin 80 mg after non-cardioembolic stroke/TIA reduces recurrent stroke; hemorrhagic-stroke signal HR 1.66.
DECIMAL2007
Hemicraniectomy within 30 h cuts mortality 52.8 pp in malignant MCA infarction (age <56).
PREMIUM2017
Sham-controlled Amplatzer trial: efficacy co-primary not met, safety co-primary met.